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The science behind autophagy: how fasting unlocks the cleansing powers of the human body

In 2016, Japanese cell biologist Yoshinori Ohsumi was awarded the Nobel Prize in Physiology or Medicine for his groundbreaking studies on autophagy, a field that has become one of the core sciences of health today. The

word “autophagy” comes from the Greek words “auto-” meaning self- and “phagy-” meaning to eat-translating as “self-eating.” This important cellular process enables the body to clear out parts of itself that have been damaged, remove aged cells, and even possibly harmful material, including malignant cells and neurodegenerative diseases linked to toxins in the brain such as Alzheimer’s disease.

Autophagy results from stress, especially during food abstention or a state of calorie shortage. The body enters into a shift from energy storage to energy conservation in the absence of food, and cells start to recycle damaged or unnecessary components for survival. This will not only ensure energy utilization at an optimum level but also facilitate cellular repair and renewal for making the body resilient over time.

The discovery of autophagy, by Ohsumi, made the finding an unexpectedly powerful natural defense system well beyond the maintenance of energy. It could hold the potential for decelerating aging, diminishing inflammation, and enhancing immunity. Moreover, continuing studies show that provoking autophagy via habits related to IF may avoid or even reverse some conditions, including tumors, diabetes, and degenerating brain diseases.

How to Stimulate Autophagy

1. Intermittent Fasting: This is cycling between periods of eating and periods of fasting; one popular method is the 16:8, in which one fasts for 16 hours and eats within an 8-hour window.
2. Prolonged Fasting: Extended fasting for 24-72 hours under medical supervision may have a stronger impact on autophagy.
3. Exercise: Regular physical activity can induce mild autophagy to help clean out damaged cellular components.
4. Low-Carb or Ketogenic Diets: Both can simulate fasting by lowering levels of glucose in the body, hence forcing it to use fat for energy.

Although the benefits from autophagy are promising, researchers are still wary and say that much more research is needed in order to fully understand its effects and find out the safest way to optimize the process. It’s about balance, since too much fasting can lead to adverse effects.

Autophagy is the secret to your body’s amazing adaptability and healing potential. This natural cleansing process

heralds a life of better longevity, lesser chances of disease, and health if one listens to its voice through fasting and lifestyle alterations.

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